To investigate the in vitro anthelmintic efficacy of dividivi (Caesalpinia coriaria), a traditional medicinal plant used
in Central America and the northern part of South America, extracts from the foliage of this plant were subjected
to the egg hatching test (EHT) and larval exsheathment inhibition test (LEIT), against Haemonchus contortus. Four
different extracts were evaluated: acetone-water (AW), methanol-water (MW), acetone-water-dichloromethane
(AWD) and methanol-water-dichloromethane (MWD). The concentrations used for the EHT and LEIT tests ranged
from 500 to 4000 μg mL-1 and six repetitions per concentration. The effective concentrations (EC50) were calculated
using Probit analysis. The EC50 for EHT were 2947.0, 3347.0, 3959.6 and 4538.7 μg mL-1 for MWD, MW, AW and
AWD, respectively. The EC50 for LEIT were 2883.4, 5927.4, 9876.3 and 9955.4 μg mL-1 for AWD, AW, MWD and MW,
respectively. The methanol extracts were the most effective in inhibiting the hatching of eggs, while the acetone
extracts showed efficacy in inhibiting larval exsheathment. This study explains the importance that C. coriaria has
as a medicinal plant in Central and South American countries.