This report consolidates the accomplishments and challenges of a diverse range of CIFSRF initiatives by examining common outcomes: improved nutrition, increased incomes, gender integration in research and development, and policy influence. The Canadian International Food Security Research Fund (CIFSRF) initiative promotes innovation in development through applied science and technology. CIFSRF projects have pioneered new forms of partnerships among public, private, and not-for-profit stakeholders, as well as with local business communities. Collaborations have resulted in development of nutritious foods, animal vaccines, and creative production and processing practices that have changed the lives of millions of people.